Transactions 2007 Through Monday, September 24th
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| Team Name | Replaced | Picked Up |
| Sultans of Swat | Taxi - Jeremy Bonderman | Activated - Cole Hamels |
| Rooster Rage | Taxi - Noah Lowry | Activated - Miguel Batista |
| Priory of Yawkey Way | Taxi - Carl Crawford | Activated - Mark DeRosa |
| Priory of Yawkey Way | Released - C.J. Wilson | Promoted - Homer Bailey |
| Camel Jockeys | Released - Chuck James | No Open Spot |
| Camel Jockeys | Released - Stephen Drew | Activated - Edgar Renteria |
| Camel Jockeys | Taxi - Chris Duncan | Activated - Austin Kearns |
| The Bigg Doggs | Taxi - Heath Bell | Activated - Roger Clemens |
| The Bigg Doggs | Taxi - Albert Pujols | Activated - Mike Cameron |
| A.C.L. | Taxi - Shaun Marcum | Activated - Ubaldo Jimenez |