Transactions 2006 Through Monday, September 25th
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| Team Name | Replaced | Picked Up |
| The Bigg Doggs | Taxi - Coco Crisp | Activated - Morgan Ensberg |
| Iron Men | Taxi - Derrek Lee | Activated - Ryan Shealy |
| Camel Jockeys | Taxi - Ben Sheets | Activated - Roger Clemens |
| Camel Jockeys | Released - Joe Blanton | Activated - Rich Harden |
| Sultans of Swat | Taxi - Jose Contreras | Activated - Scot Shields |
| Asian Pranksters | Released - Tim Wakefield | No Open Spot |
| Non - Smokers | Released - Matt Kemp | No Open Spot |
| Make 7up Yours | Released - Hideki Matsui | No Open Spot |
| The Bigg Doggs | Released - Jeff Mathis | No Open Spot |