Transactions 2005 Through Monday, September 19th
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| Team Name | Replaced | Picked Up |
| The Bigg Doggs | Taxi - Jose Mesa | Activated - Scot Shields |
| Winged Buffalo | Taxi - Eric Hinske | Activated - Nick Swisher |
| Winged Buffalo | Released - Jarrod Washburn | Activated - Vicente Padilla |
| Winged Buffalo | Taxi - Craig Biggio | Activated - Todd Walker |
| Non - Smokers | Released - Mike Piazza | No Open Spot |
| Non - Smokers | Released - Tyler Walker | No Open Spot |